THE BIG BANG THEORY - CBS VIDEO: 'The Isolation Permutation' Episode Trailer Airs Thursday, November 3, 2011 at 8/7C
Sheldon and Amy have something unique but Amy has a mind of her own! Is this the night Sheldon joins the human race? Tune in on Thursday, November 3rd at 8/7c on CBS!
Amy (Mayim Bialik) is crushed when Bernadette (Melissa Rauch) and Penny (Kaley Cuoco) go shopping for wedding dresses without her.
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